Clinical research
Clinical
Clinical research, diagnostics, and evidence-based naturopathic practice.
Curcumin for Depression: What a 2026 Meta-Analysis of 19 Trials Actually Shows
A 2026 systematic review and meta-analysis pooled 19 randomized controlled trials testing curcumin supplementation against placebo for depression and depressive symptoms. The pooled effect was statistically significant, but the authors' own sensitivity analysis found it fragile. This article reviews the numbers, the caveats, and what an honest reading means for naturopathic practice.
POTS (Postural Orthostatic Tachycardia Syndrome): What the Non-Drug Evidence Actually Shows
A naturopathic evidence review of POTS covering diagnostic criteria, mechanisms, and the randomized trial evidence for exercise reconditioning, compression garments, and sodium and fluid loading.
ME/CFS Functional Medicine: A Clinical Protocol Guide
ME/CFS functional medicine assessment covering IOM diagnostic criteria, post-exertional malaise, mitochondrial and immune mechanisms, pacing, and evidence-informed support.
Fibromyalgia Naturopathic Treatment: Evidence Review
Fibromyalgia naturopathic treatment evidence reviewed: central sensitisation, mitochondrial and neuroinflammatory mechanisms, CoQ10, magnesium, LDN awareness, exercise, sleep, and pacing.