Functional Testing research
Functional Testing
Functional lab testing and biomarker interpretation.
The Omega-3 Index: What the Test Measures, and Why the Cardiovascular Trial Evidence Is More Mixed Than It Looks
The Omega-3 Index is a well-validated predictor of cardiovascular risk in observational cohorts. But the randomized trial evidence on whether raising it through supplementation actually prevents cardiovascular events is genuinely mixed: one trial of purified EPA showed a large benefit, while trials of EPA+DHA blends in similar high-risk patients and in the general population did not. This article works through why, trial by trial.
IgG Food Sensitivity Testing: What the Evidence Actually Shows
IgG and IgG4 food antibody panels are widely sold as 'food sensitivity' tests in naturopathic practice. Major allergy bodies say the antibody itself is a marker of exposure and tolerance, not proof of intolerance, yet several controlled trials in IBS report real symptom benefit from IgG-guided elimination diets. Both things are true at once, and this article works through what that means in practice.
Pyrrole Disorder (Kryptopyrroluria): Evidence and Treatment
Pyrrole disorder is one of the most debated diagnoses in functional and naturopathic medicine. Here's an honest examination of the evidence, what kryptopyrole testing actually measures, its association with nutrient depletion, and the clinical picture in anxiety, ADHD, and mood disorders.